metabolomics相关论文
Background:Metabolomic approaches, which include the study of low molecular weight molecules, are an emerging-omics tech......
Integration of metabolomics and transcriptomics revealed the biosynthetic mechanism of anti-parasiti
The fermentation broth of Salinivibrio proteolyticus strain YCSC6 shows potent anti-parasitic activity against Uronema m......
Stearoyl-CoA desaturase 1 inhibitor supplemented with gemcitabine treatment reduces the viability an
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Gestational diabetes mellitus(GDM)is one of the most common metabolic disorders of pregnancy and can cause short-and lon......
本文在分析了常用的微生物代谢组学研究方法的基础上,采用UPLC-Q-TOF MS~E代谢组学技术结合主成分分析(PCA)和正交偏最小二乘判别......
代谢组学是全面系统地描述生物样本中所有小分子代谢产物的一门学科。代谢组学可以通过内源性代谢物整体反映细胞内外环境的变化，在......
目的寻找大骨节病（KBD）儿童血液中与KBD相关的差异代谢物。方法在青海省KBD病区7~15岁寄宿制学生中，通过临床检查和X线拍片，选择病区患......
目的探讨支气管肺发育不良(bronchopulmonary dysplasia，BPD)早产儿出生36 h内尿代谢产物的特点，为BPD寻找出生早期的预警指标。方法......
代谢组学通过全面、定量检测生物样本中多种类型的小分子化合物，有助于了解内、外因作用下生物体内源性物质的变化及规律，发现疾病发......
目的探讨5-羟基-1-甲基海因（HMH）对百草枯（PQ）中毒所致肾损伤的防护作用及机制。方法采用随机数字表法将15只SPF级健康昆明小鼠分为生......
目的研究低血糖指数(GI)谷物对妊娠期糖尿病(GDM)孕妇代谢组学及妊娠结局的影响，探讨其对妊娠糖尿病的防治作用机制，为制定营养干预......
目的 分析轻症急性胰腺炎(MAP)患者血清代谢组学,筛选出具有潜在临床诊断价值的代谢标志物.方法 应用超高效液相色谱与高分辨质谱......
目的探讨刺五加干预对大鼠的潜在保护/毒性作用。方法应用随机数字表法将20只雄性SD大鼠分为刺五加组和对照组，每组10只。刺五加组......
Abstract Lactic acid bacteria have been important industrial floras in the food fermentation production industry since a......
Development of High Performance Liquid Chromatography and Mass Spectrometry:a Key Engine of TCM Mode
Traditional Chinese Medicine (TCM) has been popular for thousand years in prevention and treatment of chronic diseases s......
对影响烟草代谢物提取的4个关键因素(溶剂、提取方式、提取时间、提取温度)在3个水平上进行了正交设计,确立了最佳提取方法;对色谱......
Integrated metabolo-transcriptomics and functional characterization reveals that the wheat auxin rec
Fusarium head blight (FHB) caused by Fusarium graminearum Schwabe (teleomorph Gibberella zeae (Schw.) Perch) results in ......
Objective:To demonstrate the rheumatoid arthritis(RA)mechanisms by determining the biochemi-cal changes.To investigate t......
Effect of Yinlai Decoction on the metabolic pathways in the lung of high-calorie diet-induced pneumo
Objective: To search for specific metabolites in the lungs of pneumonia rats fed with a high-calorie diet, as well as ex......
Psoriasis is considered a systemic disease associated with metabolic abnormalities, and it is important to understand th......
Metabolic profiling of DREB-overexpressing transgenic wheat seeds by liquid chromatography–mass spec
DREBs are transcription factors that regulate abiotic stress tolerance in plants. Previously, we reported that wheat tra......
Soil water deficit and salt stress are major limiting factors of plant growth and agricultural productivity. The primary......
目的探讨维康颗粒(Weikang Granule,WG)对乳腺癌小鼠肿瘤相关性疲劳的影响及代谢机制。方法将40只成功接种4T1乳腺肿瘤细胞的小鼠......
目的采用气相色谱与质谱联用技术(gas chromatography-mass spectrometer/mass spectrometer,GC-MS/MS)分析小儿支气管哮喘发作期......
Objective:Upper gastrointestinal (UGI) cancers,predominantly gastric cancer (GC) and esophageal cancer (EC),are malignan......
Residual feed intake divergence during the preweaning period is associated with unique hindgut micro
Background:Recent studies underscored that divergence in residual feed intake (RFI) in mature beef and dairy cattle is a......
,Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Pol
The main constituents of a typical medicinal herb,Polygonum muMflorum (Heshouwu in Chinese),that induces idiosyncratic l......
High-throughput metabolomics reveals the perturbed metabolic pathways and biomarkers of Yang Huang s
High-throughput metabolomics can clarify the underlying molecular mechanism of diseases via the quafitative and quantita......
系统性红斑狼疮(SLE)是一种以自身抗体产生和免疫复合物形成为特点的自身免疫性疾病.其临床表现多种多样,包括肾小球肾炎、皮肤炎......
代谢组学技术应用于自身免疫性疾病的研究，筛选出的代谢物不仅能够反映葡萄糖、氨基酸和脂代谢，还能够反映神经递质、核苷酸、免疫应......
Effects of moxibustion and acupuncture at Zusanli (ST 36) and Zhongwan (CV 12) on chronic atrophic g
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Integration of lipidomics and metabolomics for in-depth understanding of cellular mechanism and dise
Mass spectrometry (MS)-based omics technologies are now widely used to profile small molecules in multiple matrices to c......
目的 分析新生大鼠坏死性小肠结肠炎(necrotizing enterocolitis,NEC)肠道内容物代谢轮廓的变化和特征,探讨潜在的NEC生物标志物.......
目的检测病情严重程度不同的急性胰腺炎(AP)患者尿液小分子代谢物谱，筛选对AP及其严重程度具有潜在诊断价值的差异代谢物。方法收集......
With increasing emission of silver nanoparticles (AgNPs) into the environment,it is important to understand the effects ......
目的运用代谢组学方法研究参麦方对于由阿霉素所造成的大鼠心肌损伤的保护作用,探讨参麦方在体内发挥药效的作用机制。方法通过超......
1H-NMR based metabolomics approach to evaluate effect of Cydonia obIanga Miller total flavonoid on a
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Effect and mechanism of Huanglianjiedu decoction on high fat-induced atherosclerosisrats and metabol
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Chemometric identification of canonical metabolites linking critical process parameters to monoclona
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的基于代谢组学的方法研究决明子水提物（AESC）对大鼠尿液内源性代谢产物的影响。方法雄性SD大鼠28只随机分成正常对照组、AESC 1.5......
Biomarker and pathway analyses of urine metabolomics dairy cows when corn stover replaces alfalfa ha
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Integrative analysis of indirect calorimetry and metabolomics profiling reveals alterations in energ
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
代谢组学是继基因组学、转录组学和蛋白质组学之后新近发展起来的一门学科，主要对生物或细胞在某一时期内产生的小分子质量代谢产物......
Milk production and composition and metabolic alterations in the mammary gland of heat-stressed lact
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
